Exchange – Office 365 Hybrid Configuration Wizard Can’t Start
The Exchange – Office 365 Hybrid Configuration Wizard application may not run as expected due to IE security settings for ClickOnce type applications, and the web page provides a link to the Wizard app which visits a few another URL’s until it reaches to the executable.
There are workarounds on the Internet, that shows adding domains to Trusted Zone and Change IE Security settings for Downloaded files etc. But they may not help you on Windows Server 2016, and if you don’t want to spend more time for this one time requirement: you can download the target file by using this link.
Visit this link first https://configure.office.com/Scenario.aspx?sid=33 to open
Hope it helps